University of Bath spinout launched to improve lung cancer treatment

Prothea Technologies, a new spinout company from the universities of Bath and Edinburgh, has launched aiming to enable lung cancer biopsy and treatment in a single visit.

The firm has attracted £10.3 million of investment as it looks to develop a device which can quickly diagnose lung cancer lesions.

This device uses a combined endoscope and image-processing system capable of examining the molecular structure of lung lesions.

The team is also looking into a laser-ablation catheter to treat lesions immediately after diagnosis, reducing time-to-treatment from weeks to minutes.

This would also relieve hospital pressures and improve patient outcomes.

Stepping up as CTO of Prothea is Dr Jim Stone from Bath’s Department of Physics.

“Establishing Prothea Technologies is essential to bring our unique fibre optic technology into clinic so it can benefit patients”, said Dr Stone.

“Prothea pulls together world-leading fibre-optic development from the University of Bath and clinical excellence from the University of Edinburgh – adding in commercial, insight, expertise and know-how to form a fantastic team.

“I’d like to thank everyone who’s played their part to get us this far – our investors Earlybird Venture Capital and Merieux Equity Partners, with participation from NRW.BANK and Old College Capital.

“I’d also like to particularly thank the Engineering and Physical Sciences Research Council (EPSRC), which funded significant academic research programmes and industrially focused grants.”

Lung cancer is one of the most common types of cancer and is the world’s deadliest form of cancer, responsible for more than two-million deaths per year.

With its planned devices, the firm aims to tackle two challenges in the management of the disease – inaccurate biopsies and limited treatment options for small lesions in the lungs.

The funding raised will finance the company’s first-in-human clinical trials for the real-time imaging and biopsy device, and move towards beginning trials for the laser ablation catheter.

The company is led by CEO and executive chair Crispin Simon – formerly president of the endoscopy division of the medical technology company Smith+Nephew – as well as Dr Kev Dhaliwal, professor of molecular imaging and healthcare technology and consultant in respiratory medicine at the Royal Infirmary of Edinburgh.

Crispin said: “We’re delighted to have been able to combine a great team, multiple technology innovations and a strong investment syndicate, and look forward to putting our products at the service of doctors and their patients.”

Professor Dhaliwal, chief medical officer and chief scientific officer at Prothea, added: “Molecular-level data capture, combined with immediate therapy, holds huge potential in basic science and patient therapy.

“I’m grateful to the funders who’ve backed us over the years.”